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vivacell_graurotbuttonklein  Recent news

May 2016

We were awarded the Stifterverband's "Innovative through Research" for our research activities.

 

April 2016

New Version of SimDerma including 30 important dermato-cosmetic parameters.

Read more here.

 

November 2015:

New Services in neurotoxicity and neuroprotection

Read more here.

 

October 2015:

SimDerma - new screening platform for cosmetic ingredients.

simderma_werbefoto

Read more here.

 

Services in Oral Care.

Read more here.

 

September 2015:

Please have a look at our new services in miRNA research.

Read more here.

 


 

New publications by VivaCell:

 

"Poly(I:C) increases the expression of mPGES-1 and COX-2 in rat primary
microglia."

in J Neuroinflamm. 2016 Jan

 

"Antimalarial Drug Artemether Inhibits Neuroinflammation in BV2 Microglia
Through Nrf2-Dependent Mechanisms."

in Mol Neurobiol. 2015 Nov

 

"microRNA-26a modulates inflammatory response induced by toll-like receptor 4 stimulation in microglia."

in J Neurochem, 2015 Sep

 

"Anti-inflammatory effects of 5-HT3 receptor antagonists in interleukin-1beta stimulated primary human chondrocytes."
in Int Immunopharmacol. 2014 Jun

"Histone deacetylase inhibitors valproic acid and sodium butyrate enhance prostaglandins release in lipopolysaccharide-activated primary microglia."
Neuroscience. 2014 Jan 28

 

 

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vivacell_graurotbuttonklein  Opinions from our customers:

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Dr. G. Weiss (PASCOE pharmazeutische Praeparate GmbH):

:

"During our well going cooperation over several years, we learned to appreciate VivaCell as a reliable and competent co-operation partner in pre-clinical research. Therefore we are looking forward to continue our successful partnership."  

 

 

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opinions...

 

 

Phytodrug / Nutraceuticals
Immunomodulation
Cardiovascular inflammation
Oncology / Angiogenesis
Oral care
Central Nervous System
Microglia activation studies
Electrophysiological. Meas.
Dermatology / Cosmetics
Muscle
HIV-1 / AIDS
Diabetes
ADME
Permeability Studies
Toxicology
Urinary / Prostata
Animal health
Additional Services
Quality Certificate
SimDerma / Cosmetics
Neurotox testing / Protection
miRNA
Services in Oral Care

 

We are awarded for our R&D activities by the Stifterverband:

 

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We are proud members of:

 

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    koop-phyto-logo

ga 

 

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VivaCell Quality-Certificate:

 

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 MUSCLE

  muscle


In vivo models adapted for Nutraceutical Research

- Myotoxicity: experimental myological alterations induced by different chemical toxicants.
- Muscle hypertrophy: treadmill running, surgical ablation of a muscle synergist.
- Muscle atrophy: denervation (chronic or transient), immobilisation, tenotomy, …
- Muscle degeneration and regeneration: several experimental procedures are available: chemical (intramuscular injection of toxins or local anaesthetics) and physical (cold, contusion, strains, exercise),..
- Exercise: chronic and acute exercise; eccentric and concentric exercise,..
- Nutrition: deprivation, hypocaloric and hypoproteic diets
Muscle ageing: study of sarcopenia (gradual loss of muscle fibres and decrease in fibre size) in several muscles.

 

Parameters:
- Histological techniques (H&E, modified Gomor trichrome, Van Giesson, toluidine blue for semithin sections,…)
- Histochemical techniques (PAS, Oil Red O, NADH-tr, myofibrilar ATPase, SDH, acid phosphatase, alkaline phosphatase, phosphorylase, ..)
- Inmunohistochemical techniques (myosin isoforms, desmin, MyoD, myogenin, etc…)
- Electron microscopic analysis: ultrastructural morphology
Morphometric analysis: muscle fibre size (area and minimum diameter), form factor, fibre types frequency, capillary density, incidence of pathologically altered muscle fibres, ultrastructural morphometry,…

 

 

 

 

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