^{Recent news}

"Pharmacological inhibition of Akt and downstream pathways modulates the

expression of COX-2 and mPGES-1 in activated microglia." - Published in:
J Neuroinflammation

2012 Jan 3

^{Opinions from our customers:}

Dr. G. Weiss (PASCOE pharmazeutische Praeparate GmbH):

"We cooperate very well since many years and learned to appreciate VivaCell as a reliable and competent co-operation partner in pre-clinical research. Therefore we are looking forward to continue our successful partnership."

Publications - Metabolism

2004

Friedrich G, Appel K, Rose T, Wangemann M, Althaus M, Rissler K. Determination of dihydroergocryptine in human plasma and urine samples using on-line sample extractioncolumn- switching reversed-phase liquid chromatography-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2004 Sep 5;808(2):131-9.

2003

Gomez-Lechon MJ, Donato MT, Castell JV, Jover R. Human hepatocytes as a tool for studying toxicity and drug metabolism. Curr Drug Metab. 2003 Aug;4(4):292-312. Review.

2000

Althaus M, Retzow A, Castell JV, Gomez-Lechon MJ, Amalou Z, Rose T, Appel K. In vitro identification of the cytochrome P450 isoform responsible for the metabolism of alphadihydroergocryptine. Xenobiotica. 2000 Nov;30(11):1033-45.

Rodriguez-Antona C, Jover R, Gomez-Lechon MJ, Castell JV. Quantitative RT-PCR measurement of human cytochrome P-450s: application to drug induction studies. Arch Biochem Biophys. 2000 Apr 1;376(1):109-16.