Phytodrugs / Nutraceuticals

Immunology / Inflammation / AIDS

CNS

Cancer / Oncology

Metabolism

Chemistry

Aktuelle Veröffentlichungen

Publications - Cancer/Oncology

 

2005

 

Aiello A, Fatorusso E, Luciano P, Macho A, Menna M, Muñoz E. Antitumoral effects of two novel unique naturally occurring terpene quinones isolated from the Mediterranean ascidian Aplidium Conicum. J.Med-Chem. 2005 In press.

 

Pajonk F, Scholber J, Fiebich B. Hypericin-an inhibitor of proteasome function. Cancer Chemother Pharmacol. 2005 May;55(5):439-46. Epub 2005 Jan 26.

 

2004

 

Macho A, Blanco-Molina M, Spagliardi P, Appendino G, Bremner P, Heinrich M, Fiebich BL, Muñoz E. Identification of Ca2+ Ionophoretic and Apoptotic Daucanes from Giant Fennel (Ferula communis L.). Biochem. Pharmacol. 2004 Sep 1;68(5):875-83.

 

2003 and before

 

Sancho R, de la Vega L, Appendino G, Di Marzo V, Macho A, Munoz E. The CB1/VR1 agonist arvanil induces apoptosis through an FADD/caspase-8-dependent pathway. Br J Pharmacol. 2003 Nov;140(6):1035-44. Epub 2003 Oct 6.

 

Macho A, Sancho R, Minassi A, Appendino G, Lawen A, Munoz E. Involvement of reactive oxygen species in capsaicinoid-induced apoptosis in transformed cells. Free Radic Res. 2003 Jun;37(6):611-9.

 

Macho A, Lucena C, Sancho R, Daddario N, Minassi A, Munoz E, Appendino G. Nonpungent capsaicinoids from sweet pepper synthesis and evaluation of the chemopreventive and anticancer potential. Eur J Nutr. 2003 Jan;42(1):2-9.

 

Blanco-Molina M, Tron GC, Macho A, Lucena C, Calzado MA, Munoz E, Appendino G. Ingenol esters induce apoptosis in Jurkat cells through an AP-1 and NF-kappaB independent pathway. Chem Biol. 2001 Aug;8(8):767-78.

 

Gajate C, Santos-Beneit AM, Macho A, Lazaro MC, Hernandez de Rojas A, Modolell M, Muñoz E, Mollinedo F. Involvement of mitochondria and caspase-3 in ET-18-OCH3 induced apoptosis of human leukemic cells. Int. J. Cancer 2000 86, 208-218